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Fenugreek

Herbal seed extract

Also known as Trigonella foenum-graecum, Testofen, methi, fenugreek seed extract, Furosap

A kitchen spice whose seed extracts are sold to men for testosterone. Seven trials pooled show a small rise in total testosterone (SMD 0.32), most of it from branded extracts with manufacturer involvement. The better-founded effect is on blood sugar in people with diabetes.

What doses have been studied? What each trial gave, with the population it was given to.

Guide updated Oct 22, 2026Literature checked Oct 22, 20266 curated studies28 literature recordsBaseline editorial

Overview

In shortFenugreek is a curry spice whose seed extracts are sold to men for testosterone. Two literatures sit side by side: an older one on blood sugar in diabetes, where the pooled trials find real reductions, and a newer, smaller one on testosterone and strength, mostly from branded extracts, where the effect is real but small.

Fenugreek is a legume whose seeds flavor curries and whose extracts fill testosterone-booster capsules. The seeds carry steroidal saponins, diosgenin in particular, which is why plant-steroid language attaches to it.

Two literatures sit side by side. The older one is about blood sugar: fenugreek seed has been tested in people with diabetes for decades and the pooled trials find lower fasting glucose and HbA1c. The newer, smaller one is about men, testosterone and strength, mostly in trials of branded extracts, and the effect it finds is real but small.

Mechanism

In shortThe seed's steroid-like saponins are proposed to block the enzymes that convert testosterone into estrogen and DHT, leaving more testosterone around. The blood sugar effect comes from fiber and an amino acid that slow sugar absorption and act on insulin. The trials measured hormones and glucose, not the mechanism.

The saponins and their aglycone diosgenin are proposed to act on steroid synthesis, and on aromatase and 5-alpha-reductase, the enzymes that turn testosterone into estradiol and DHT. Inhibiting those would leave more testosterone in circulation. The glucose effect runs through a different set of constituents, soluble fiber and the amino acid 4-hydroxyisoleucine, which slow carbohydrate absorption and act on insulin release. None of the human trials measured the mechanism; they measured the hormone or the glucose.

Evidence

In shortSeven trials pooled, 449 people, show a small rise in total testosterone (SMD 0.32); strength and lean mass lean the same way without reaching significance. The branded 120-man trial reports testosterone up with no numbers. An independent 95-man trial found a 13% rise that was not significant against placebo. Fourteen trials in diabetes found HbA1c 0.88 points lower.

Testosterone. A 2023 meta-analysis of seven studies with 449 participants (378 men) found a small effect on total testosterone (SMD 0.32, 95% CI 0.09 to 0.55) in male athletes, with free testosterone, lean mass, fat mass and leg press all pointing the same way but not reaching significance. A 2020 meta-analysis of four trials also found a significant effect on total testosterone, with no numbers in its abstract.

The branded trial. 120 healthy men aged 43 to 70 took 600 mg a day of a standardized extract or placebo for 12 weeks. Aging-male symptom scores fell, morning erections and sexual activity increased, and total and free testosterone rose against placebo. No numbers in the abstract.

The independent dose-ranging trial. 95 men aged 40 to 80 took 0, 600, 1,200 or 1,800 mg a day of another extract for 12 weeks. Plasma testosterone rose 13% from baseline on any dose but not significantly against placebo (9%); saliva testosterone rose 37.2% against placebo. Read against the branded trial, this is what a modest effect looks like when the placebo arm is reported honestly.

Blood sugar. Fourteen trials in 894 people found HbA1c 0.88 percentage points lower with fenugreek; fasting and post-meal glucose moved in the same direction without reaching significance, with quality and heterogeneity flagged. A separate 12-trial meta-analysis found fasting glucose 12.9 mg/dL lower, HbA1c 0.58 points lower, and total and LDL cholesterol lower.

Safety

In shortWell tolerated in the trials, with no side effects at up to 1,800 mg a day. It lowers blood sugar, so it stacks with diabetes drugs, and it is related to peanuts and chickpeas, so allergy happens. It makes sweat smell of maple syrup, which is harmless. Pregnancy is a traditional no.

The trials report it as well tolerated, and the dose-ranging trial saw no side effects at up to 1,800 mg a day for 12 weeks. Fenugreek is a food, and the extract doses in trials are within what a curry-heavy diet delivers in seed.

Three practical cautions. It lowers blood sugar, so it adds to diabetes drugs. It is a legume related to peanuts and chickpeas, and allergy has been reported. And it gives sweat and urine a maple-syrup smell, which is harmless but alarming if you were not warned. Pregnancy is a traditional contraindication because of effects on the uterus in animals; no trial here addresses it.

Regulatory status

In shortA food and a supplement in the US, UK and EU, with no claims reviewed. The testosterone and blood sugar effects the trials show are not claims a label may make, and no extract is licensed as a medicine.

A food and a dietary supplement in the United States, the United Kingdom and the European Union, with no claims reviewed. The testosterone and glucose claims the trials support are not claims a supplement label may make. No regulator has licensed any fenugreek extract as a medicine for either purpose.

The literature

6 studies indexed. Findings and limitations get equal weight, on purpose.

Always check the primary source

Members area

The Fenugreek literature needs an account

Everything above is free to read. What an account opens is the evidence underneath it: 6 studies with their limitations, and the regimen each trial actually reported.

  • Every study, with what it found and what it cannot show
  • The limitations, given the same weight as the findings
  • The dose each named trial administered, where recorded

Free to create. A membership is separate, and you can decide about that later.

Reading is free, an account is not the same as paying. 80 compound guides, every study with its limitations written underneath, and the regimens those trials actually used. A free account opens all of it. A membership is a separate decision, and it opens the forum. What membership costs.

The wider literature

14 indexed papers and 14 registered trials mentioning Fenugreek, straight from PubMed and ClinicalTrials.gov. 11 of 14 administer it; the rest measure it. These have not been read by us. Unlike the studies above, they carry no findings and no limitations written by anyone here, because writing either would mean claiming a reading nobody has done. They are a starting point for yours.

Registered trials (14)

  1. Effect of Fenugreek Seed Administration on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion

    University of Guadalajara2025NCT07056712

    interventionalnanot yet recruitingn=28

  2. A Study to Assess the Effect of Libifem® (VL-GF-01) on Fertility in Women With Diminished Ovarian Reserve

    Vedic Lifesciences Pvt. Ltd.2025NCT06826716

    interventionalnanot yet recruitingn=150

  3. Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms

    RDC Clinical Pty Ltd2023NCT05795816

    interventionalphase3completedn=150

  4. Determining the Lipid Lowering Effect of Fenugreek Seed Tea

    Queen's University, Belfast2023NCT05858671

    interventionalnacompletedn=67

  5. Dog-rose, Cranberry Leaves, Cranberry Berries, Alfalfa, Fenugreek, Lemon Beebrush, Urtica and Sumac in Diabetes Mellitus

    Tabriz University of Medical Sciences2023NCT05700513

    interventionalphase1phase2unknownn=60

  6. Effect of Raw Versus Roasted Fenugreek Seed Powder in Reducing Blood Glucose Levels in Type 2 Diabetic Patients

    University of Veterinary and Animal Sciences, Lahore - Pakistan2022NCT05550870

    interventionalnacompletedn=35

  7. Relevance of Sensitization to Fenugreek in Children

    Central Hospital, Nancy, France2022NCT05340920

    observationalunknownn=50

  8. Effect of Testofen on Erectile Function in an Adult Male Population

    RDC Clinical Pty Ltd2022NCT05232279

    interventionalphase3active not recruitingn=120

  9. Efficacy and Safety of Milk Secretory Supplement in Breast-feeding Volunteers

    Chulalongkorn University2022NCT05880589

    interventionalnaunknownn=24

  10. The Efficacy of Fenugreek Supplementation on Men's Health

    Jacksonville University2017NCT03528538

    interventionalnacompletedn=58

  11. Efficacy and Safety of Fenugreek Extract on Markers of Muscle Damage and Inflammation in Untrained Males

    University of Mary Hardin-Baylor2017NCT03318731

    interventionalnacompletedn=60

  12. Effect of Fenugreek Use in Mothers of Preterm on Breast Milk Production and Macronutrient Content

    Tel-Aviv Sourasky Medical Center2015NCT02384655

    interventionalphase1phase2unknownn=30

  13. Glycemic and Satiety Response Study of Fibre-Enriched Pudding Products

    University of Guelph2014NCT02289612

    interventionalnacompletedn=15

  14. The Efficacy Study of FUROSAP: A Testosterone Booster Supplement In Humans.

    Chemical Resources2014NCT02702882

    interventionalnacompletedn=100

Papers (14)

  1. Antidiabetic potential of fenugreek (Trigonella foenum-graecum): A magic herb for diabetes mellitus.

    Sarker DK, et al.Food science & nutrition2024PMID 39479631

    journal articlereview

  2. Effects of Trigonella foenum graecum (fenugreek) on rheumatoid arthritis: a systematic review.

    Faghfoori Z, et al.Immunopharmacology and immunotoxicology2023PMID 37039783

    systematic reviewjournal article

  3. Trigonella foenum-graecum (fenugreek) differentially regulates antioxidant potential, photosynthetic, and metabolic activities under arsenic stress.

    Ahmad J, et al.Ecotoxicology and environmental safety2022PMID 36193587

    journal article

  4. Determination of Bioactive Compounds of Fenugreek (Trigonella foenum-graecum) Seeds Using LC-MS Techniques.

    Singh P, et al.Methods in molecular biology (Clifton, N.J.)2020PMID 31893460

    journal article

  5. Fenugreek (Trigonella foenum-graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice.

    Tewari D, et al.Nutrients2020PMID 32846876

    journal article

  6. Amebicidal effects of fenugreek (Trigonella foenum-graecum) against Acanthamoeba cysts.

    Kaya Y, et al.Food science & nutrition2019PMID 30847135

    journal article

  7. 4-Hydroxyisoleucine from Fenugreek (Trigonella foenum-graecum): Effects on Insulin Resistance Associated with Obesity.

    Avalos-Soriano A, et al.Molecules (Basel, Switzerland)2016PMID 27879673

    journal articlereview

  8. Anti-inflammatory activity of fenugreek (Trigonella foenum-graecum Linn) seed petroleum ether extract.

    Pundarikakshudu K, et al.Indian journal of pharmacology2016PMID 27756958

    journal article

  9. Toxicological properties of fenugreek (Trigonella foenum graecum).

    Ouzir M, et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association2016PMID 27498339

    journal articlereview

  10. Efficacy of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst) in Polycystic Ovary Syndrome (PCOS).

    Swaroop A, et al.International journal of medical sciences2015PMID 26516311

    journal articlemulticenter studyrandomized controlled trial

  11. Trigonella foenum-graecum L. seed mucilage-gellan mucoadhesive beads for controlled release of metformin HCl.

    Nayak AK, et al.Carbohydrate polymers2014PMID 24702915

    journal article

  12. Effect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials.

    Neelakantan N, et al.Nutrition journal2014PMID 24438170

    journal articlemeta-analysisresearch support, non-u.s. gov't

  13. Fenugreek.

    2012PMID 31644133

    review

  14. Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues.

    Baquer NZ, et al.Journal of biosciences2011PMID 21654091

    journal articleresearch support, non-u.s. gov'treview

Discussion

Fenugreek has its own forum, and sits in Testosterone & Hormones. Every post says what kind of claim it makes.

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For Research & Educational Discussion Only. Not Medical Advice

This guide is educational reference material compiled from published literature. It is not medical advice, not a recommendation, and not a substitute for a clinician who knows your history. Nothing here should be used to make a decision about your own health without one.

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